Mazzoni Center is the only health care provider in the Philadelphia region specifically targeting the unique health care needs of the lesbian, gay, bisexual, and transgender communities. It was founded in 1979 as an all-volunteer clinic to serve the needs of sexual minorities in Philadelphia. When the first cases of HIV/AIDS began to appear in the early 1980s, the organization quickly responded, becoming the oldest AIDS service organization in the Commonwealth of Pennsylvania, and the fourth-oldest in the nation. As it grew and evolved to meet the needs of our constituents, Mazzoni Center combined HIV/AIDS-related services with a broad continuum of health care and supportive services, which include: outreach, prevention, education, direct medical and care services, psychosocial services, legal services, and support groups. With over 35,000 individuals benefiting annually from our services, we have proven ourselves to be a leader among community-based organizations in the greater Philadelphia area, and have developed a reputation for excellence and innovation in service delivery to our constituents.